Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

Author:

Wang Kai1,Baldassano Robert2,Zhang Haitao1,Qu Hui-Qi34,Imielinski Marcin1,Kugathasan Subra5,Annese Vito67,Dubinsky Marla38,Rotter Jerome I.38,Russell Richard K.9,Bradfield Jonathan P.1,Sleiman Patrick M.A.1,Glessner Joseph T.1,Walters Thomas10,Hou Cuiping1,Kim Cecilia1,Frackelton Edward C.1,Garris Maria1,Doran James1,Romano Claudio11,Catassi Carlo12,Van Limbergen Johan1013,Guthery Stephen L.14,Denson Lee15,Piccoli David2,Silverberg Mark S.16,Stanley Charles A.17,Monos Dimitri18,Wilson David C.19,Griffiths Anne10,Grant Struan F.A.120,Satsangi Jack13,Polychronakos Constantin34,Hakonarson Hakon120

Affiliation:

1. Center for Applied Genomics,

2. Division of Gastroenterology, Department of Pediatrics,

3. Department of Pediatrics and

4. Department of Human Genetics, McGill University, Montreal, Québec, CanadaH3H 1P3,

5. Department of Pediatrics, Emory University School of Medicine and Children's Health Care of Atlanta, Atlanta, GA, USA,

6. Unit of Gastroenterology, IRCCS-CSS Hospital, S. Giovanni Rotondo, Italy and

7. Unit of Gastroenterology, University Hospital Careggi, Florence, Italy, on behalf of SIGENP,

8. Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA,

9. Department of Paediatric Gastroenterology, Yorkhill Hospital, Glasgow, Scotland, UK,

10. The Hospital for Sick Children and

11. Department of Pediatrics, University of Messina, Messina, Italy,

12. Unit of Pediatrics, Università Politecnica delle Marche, Ancona, Italy,

13. Gastrointestinal Unit, Western General Hospital and

14. Department of Pediatrics, University of Utah School of Medicine and Primary Children's Medical Center, Salt Lake City, UT, USA,

15. Division of Gastroenterology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA and

16. Mount Sinai Hospital IBD group, Dr. Zane Cohen Digestive Diseases Clinical Research Centre, University of Toronto, Toronto, Ontario, Canada,

17. Division of Endocrinology, Department of Pediatrics and

18. Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA,

19. Child Life and Health, University of Edinburgh, Edinburgh, UK,

20. Department of Pediatrics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

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