This chapter aims to shed light on systemic defiance from a pluralist perspective. It first explains what is meant by pluralism here and what normative advantages are expected to flow from it. Secondly, the chapter outlines a pluralist take on the EU. This then flows into an examination of what counts as systemic defiance in a pluralist constellation and what special challenges the latter poses to the identification and remedying mechanisms. By way of conclusion, the chapter addresses the question of the extent to which pluralism is at all a viable theoretical framework for addressing the challenges of systemic defiance in the EU.