Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates-Reference-Cited by-同舟云学术

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

Published:2010-07-08 Issue:20 Volume:38 Page:7100-7111
ISSN:1362-4962
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Straarup Ellen Marie,Fisker Niels,Hedtjärn Maj,Lindholm Marie W.,Rosenbohm Christoph,Aarup Vibeke,Hansen Henrik Frydenlund,Ørum Henrik,Hansen Jens B. Rode,Koch Troels

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/38/20/7100/16767806/gkq457.pdf

Reference39 articles.

1. Short antisense oligonucleotides with novel 2′-4′ conformationaly restricted nucleoside analogues show improved potency without increased toxicity in animals;Seth;J. Med. Chem.,2009

2. Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals;Swayze;Nucleic Acids Res.,2007

3. An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis;Crooke;J. Lipid Res.,2005

4. Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol;Nishina;Mol. Ther.,2008

5. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAS;Soutschek;Nature,2004

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