Using the comet assay and lysis conditions to characterize DNA lesions from the acrylamide metabolite glycidamide

Author:

Hansen Siri Helland1,Pawlowicz Agnieszka J2,Kronberg Leif2,Gützkow Kristine Bjerve13,Olsen Ann-Karin13,Brunborg Gunnar13

Affiliation:

1. Department of Molecular Biology, Norwegian Institute of Public Health, Oslo, Norway

2. Laboratory of Organic Chemistry, Åbo Akademi University, Turku, Finland

3. Centre for Environmental Radioactivity (CERAD CoE), Ås, Norway

Funder

European Commission

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Toxicology,Genetics

Reference71 articles.

1. Analysis of acrylamide, a carcinogen formed in heated foodstuffs;Tareke;J. Agric. Food Chem,2002

2. Hemoglobin adducts as a measure of variations in exposure to acrylamide in food and comparison to questionnaire data;Vikström;Food Chem. Toxicol,2012

3. Hemoglobin adducts and mercapturic acid excretion of acrylamide and glycidamide in one study population;Hartmann;J. Agric. Food Chem,2008

4. Safety evaluation of certain contaminants in food. Prepared by the Sixty-fourth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA);JEFCA;FAO Food Nutr. Pap,2006

5. Metabolism and hemoglobin adduct formation of acrylamide in humans;Fennell;Toxicol. Sci,2005

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