Evolution of Conformational Dynamics Determines the Conversion of a Promiscuous Generalist into a Specialist Enzyme-Reference-Cited by-同舟云学术

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Evolution of Conformational Dynamics Determines the Conversion of a Promiscuous Generalist into a Specialist Enzyme

Published:2014-10-13 Issue:1 Volume:32 Page:132-143
ISSN:0737-4038
Container-title:Molecular Biology and Evolution
language:en
Short-container-title:Molecular Biology and Evolution

Author:

Zou T.,Risso V. A.,Gavira J. A.,Sanchez-Ruiz J. M.,Ozkan S. B.

Publisher

Oxford University Press (OUP)

Subject

Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Link

http://academic.oup.com/mbe/article-pdf/32/1/132/9592856/msu281.pdf

Reference78 articles.

1. Functional metagenomics reveals diverse β-lactamases in a remote Alaskan soil

2. Protonation of the -lactam nitrogen is the trigger event in the catalytic action of class A -lactamases

3. Anisotropy of Fluctuation Dynamics of Proteins with an Elastic Network Model

4. Perturbation-Response Scanning Reveals Ligand Entry-Exit Mechanisms of Ferric Binding Protein

5. Manipulation of Conformational Change in Proteins by Single-Residue Perturbations

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1. The Evolution of the Acylation Mechanism in β-Lactamase and Rapid Protein Dynamics;ACS Catalysis;2024-08-28

2. Mechanistic conformational and substrate selectivity profiles emerging in the evolution of enzymes via parallel trajectories;Nature Communications;2024-08-16

3. Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately;Science Advances;2024-06-21

4. Frustration can Limit the Adaptation of Promiscuous Enzymes Through Gene Duplication and Specialisation;Journal of Molecular Evolution;2024-03-12

5. Friends and relatives: insight into conformational regulation from orthologues and evolutionary lineages using KIF and KIN;Faraday Discussions;2024

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