Pretest Prediction of BRCA1 or BRCA2 Mutation by Risk Counselors and the Computer Model BRCAPRO

Author:

Euhus David M.,Smith Kristin C.,Robinson Linda,Stucky Amy,Olopade Olufunmilayo I.,Cummings Shelly,Garber Judy E.,Chittenden Anu,Mills Gordon B.,Rieger Paula,Esserman Laura,Crawford Beth,Hughes Kevin S.,Roche Connie A.,Ganz Patricia A.,Seldon Joyce,Fabian Carol J.,Klemp Jennifer,Tomlinson Gail

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Oncology

Reference30 articles.

1. Easton DF, Ford D, Bishop DT. Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. Am J Hum Genet1995;56:265–71.

2. Ford D, Easton DF, Stratton M, Narod S, Goldgar D, Devilee P, et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. Am J Hum Genet1998;62:676–89.

3. Schubert EL, Lee MK, Mefford HC, Argonza RH, Morrow JE, Hull J, et al. BRCA2 in American families with four or more cases of breast or ovarian cancer: recurrent and novel mutations, variable expression, penetrance and the possibility of families whose cancer is not attributable to BRCA1 and BRCA2. Am J Hum Genet1997;60:1031–40.

4. Thorlacius S, Sigurdsson S, Bjarnadottir H, Olafsdottir G, Jonasson JG, Tryggvadottir L, et al. Study of a single BRCA2 mutation with a high carrier frequency in a small population. Am J Hum Genet1997;60:1079–84.

5. Dorum A, Heimdal K, Hovig E, Inganas M, Moller P. Penetrance of BRCA1 1675delA and 1135insA with respect to breast cancer and ovarian cancer. Am J Hum Genet1999;65:671–9.

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