Scientific realism has traditionally maintained that our best scientific theories can be regarded as more or less true and as representing the world as it is (more or less). However, one of our very best current theories—quantum mechanics—has famously resisted such a realist construal, threatening to undermine the realist stance altogether. The chapters in this volume carefully examine this tension and the reasons behind it, including the underdetermination generated by the multiplicity of formulations and interpretations of quantum physics, each presenting a different way the world could be. Authors in this volume offer a range of alternative ways forward: some suggest new articulations of realism, limiting our commitments in one way or another; others attempt to articulate a ‘third way’ between traditional forms of realism and antirealism, or are critical of such attempts. Still others argue that quantum theory itself should be reconceptualised, or at least alternative formulations should be considered in the hope of evading the problems faced by realism. And some examine the nature of these issues when moving beyond quantum mechanics to quantum field theory. Taken together they offer an exciting new set of perspectives on one of the most fundamental questions in the philosophy of modern physics: how can one be a realist about quantum theory, and what does this realism amount to?