CeAid: a smartphone application for logging and plotting Caenorhabditis elegans assays

Author:

Sohrabi Salman1,Moore Rebecca S1ORCID,Murphy Coleen T1

Affiliation:

1. Department of Molecular Biology & LSI Genomics, Princeton University, Princeton, NJ 08544, USA

Abstract

Abstract Caenorhabditis elegans is used as a model organism to study a wide range of topics in molecular and cellular biology. Conventional C. elegans assays often require a large sample size with frequent manipulations, rendering them labor-intensive. Automated high-throughput workflows may not be always the best solution to reduce benchwork labor, as they may introduce more complexity. Thus, most assays are carried out manually, where logging and digitizing experimental data can be as time-consuming as picking and scoring worms. Here we report the development of CeAid, C. elegans Application for inputting data, which significantly expedites the data entry process, utilizing swiping gestures and a voice recognition algorithm for logging data using a standard smartphone or Android device. This modular platform can also be adapted for a wide range of assays where recording data is laborious, even beyond worm research.

Funder

Glenn Foundation for Medical Research

NIH

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology

Reference17 articles.

1. C. elegans behavior of preference choice on bacterial food;Abada;Mol Cells,2009

2. A semi-automated system based on level sets and invariant spatial interrelation shape features for Caenorhabditis elegans phenotypes;Abdelsamea;J Visual Commun Image Represent,2016

3. Odorant-selective genes and neurons mediate olfaction in C. elegans;Bargmann;Cell,1993

4. Resolving coiled shapes reveals new reorientation behaviors in C. elegans;Broekmans;Biochem Pharmacol,2016

5. Longitudinal imaging of Caenorhabditis elegans in a microfabricated device reveals variation in behavioral decline during aging;Churgin;Biochem Pharmacol,2017

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3