Synthesis of quinazolin-4-one and its application in some areas of bioengineering

Abstract

Until this research, many studies have been conducted with benzimidazoles and quinazolones, but there is almost no comparative information in the literature about the synthesis of 2- placed quinazolone and quinazolintion and their selective methylation under different conditions, as well as their biological activity. Therefore, among these compounds, 2-substituted It is desirable to systematically study the synthesis of quinazolin- 4-one and -thiones, to determine the factors affecting the course of reactions, to carry out some chemical changes of the obtained 2-substituted quinazolin- 4-one and -thiones and their derivatives, and to identify new biologically active compounds.