A concise formation of N-substituted 3,4-diarylpyrroles – synthesis and cytotoxic activity-Reference-Cited by-同舟云学术

A concise formation of N-substituted 3,4-diarylpyrroles – synthesis and cytotoxic activity

Published:2014 Issue:9 Volume:12 Page:1518-1524
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Egorov Maxim¹²³⁴⁵,Delpech Bernard¹²³⁴,Aubert Geneviève¹²³⁴,Cresteil Thierry¹²³⁴,Garcia-Alvarez Maria Concepcion¹²³⁴,Collin Pascal¹²³⁴⁶,Marazano Christian¹²³⁴

Affiliation:

1. Centre de Recherche de Gif

2. Institut de Chimie des Substances Naturelles

3. CNRS

4. 91198 Gif-sur-Yvette Cedex, France

5. ATLANTHERA

6. Université Paris 7 Denis Diderot

Abstract

Sequential condensation of a phenacyl halide with a primary amine and a phenylacetaldehyde led to N-substituted 3,4-diarylpyrroles. Synthesis of analogs of the marine alkaloid halitulin and cytotoxic studies are reported.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C3OB42309C

Reference39 articles.

1. Further Insight from Model Experiments into a Possible Scenario Concerning the Origin of Manzamine Alkaloids

2. Concise Access to a Model of the Marine Alkaloid Halicyclamine A through Macrocycle-Forming Addition of a 5-Aminopenta-2,4-dienal onto a 2,3-Dihydropyridinium Salt

3. On the Biosynthesis of Manzamines

4. Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms

5. Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis

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