Lead optimization through VLAK protocol: New annelated pyrrolo-pyrimidine derivatives as antitumor agents
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference18 articles.
1. Principal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitors;Lauria;J. Comp. Biol. Chem.,2009
2. Combined use of PCA and QSAR/QSPR to predict the drugs mechanism of action. An application to the NCI ACAM Database;Lauria;QSAR Comb. Sci.,2009
3. Virtual lock-and-key approach: the in silico revival of Fischer model by means of molecular descriptors;Lauria;Eur. J. Med. Chem.,2011
4. Annelated pyrrolo-pyrimidines from amino-cyano-pyrroles and BMMAs as leads for new DNA-interactive ring systems;Lauria;Bioorg. Med. Chem.,2005
5. Design and synthesis of 4-substituted Indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine derivatives with antitumor activity;Lauria;J. Med. Chem.,2008
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