Abstract
Background: Docosahexaenoic acid (DHA) has been the dominant acyl component of the membrane phosphoglycerides in neural signaling systems since the origin of the eukaryotes. In this paper, we propose, this extreme conservation, is explained by its special electrical properties. Based on the Pauli Exclusion Principle we offer an explanation on how its six methylene interrupted double-bonds provide a special arrangement of π-electrons that offer an absolute control for the precision of the energy of the signal. Precision is not explained by standard concepts of ion movement or synaptic strengthening by enhanced protein synthesis. Yet precision is essential to visual acuity, truthful recall and the exercise of a dedicated neural pathway. Concept: Synaptic membranes have been shown to actively incorporate DHA with a high degree of selectivity. During a learning process, this biomagnification will increase the proportion of membrane DHA with two consequential neuronal and synaptic enhancements which build into a David Marr type model of the real world: DHA induced gene expression resulting in enhanced protein synthesis; increased density of π-electrons which could provide memory blocks and provide for the preferential flow of a current in neural pathways. Proposal: Both the above imply memory from synaptic strengthening. We propose memory is achieved by the activation of neuronal synaptic activation with synaptic turnover resulting in enhanced membrane DHA, which in turn induces gene expression, protein synthesis and π-electron density. Repetition amplifies the process activating synapses, which form a matrix representing the memory. The electro-chemical potentials then fire the electrons as electromagnetic waves via the six methylene interrupted double bonds. These allow transmission at a specific energy level based on their quantum mechanical properties providing the precision required for faithful recall. It is difficult to conceive of protein synthesis alone providing for precision. Using the principle of the dual properties of photons and electrons we develop the idea of complex wave patterns representing the visual or auditory fields. These are likely to be non-computable. We suggest that harmonization of the electromagnetic waves can result in cohesion explaining recall and associations. The cohesion of electromagnetic flow leads to a surge above the resting level, which is recognized by the brain as, demonstrated in artificial, electrical stimulus during neurosurgery.
Subject
Agronomy and Crop Science,Biochemistry,Food Science
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