Effect of Probiotic lactobacillus Strains on Angiotensin I Converting Enzyme Inhibitory Activity from Fermented Goat Milk

Abstract

Goat milk was fermented by different strains of lactic acid bacterias in anaerobic tube, strains with high angiotensin converting enzyme (ACE) inhibitory activity were screened from 28 probiotic Lactobacillus strains by the criteria of ACE inhibitory activity and pH. The results showed that 20 strains had ACE inhibitory activity and among them the activity of 4 strains were extremely high, they were Lactobacillus reuteri, Lactobacillus bulgaricus, Lactobacillus rhamnosu and Lactobacillus helveticu. In vitro experiments, the ACE inhibitory activity of goat milk fermented by these 4 strains reached 95.92%, 84.61%, 82.79% and 78.57%, respectively. After incubation, pH of them were 6.17, 3.88, 5.24 and 3.71, respectively.