Blood-thirsty: S1PR5 and TRM-Reference-Cited by-同舟云学术

Blood-thirsty: S1PR5 and TRM

Published:2021-10-29 Issue:1 Volume:219 Page:
ISSN:0022-1007
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Hallisey Victoria M.¹,Schwab Susan R.¹^ORCID

Affiliation:

1. Skirball Institute of Biomolecular Medicine, New York University Grossman School of Medicine, New York, NY

Abstract

In this elegant study, Evrard et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20210116) find that sphingosine 1-phosphate receptor 5 (S1PR5) powerfully impairs tissue-resident memory T cell (TRM) formation, and that tissue-derived TGF-β limits S1pr5 expression by infiltrating T cells.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/doi/10.1084/jem.20211971/1424899/jem_20211971.pdf

Reference14 articles.

1. GRK2-Dependent S1PR1 Desensitization Is Required for Lymphocytes to Overcome Their Attraction to Blood

2. Finding a Way Out: S1P Signaling and Immune Cell Migration

3. Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses

4. The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection

5. Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes

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1. Tissue-Resident Memory T Cells in Gastrointestinal Cancers: Prognostic Significance and Therapeutic Implications;Biomedicines;2024-06-17

2. Role of sphingosine 1-phosphate (S1P) in sepsis-associated intestinal injury;Frontiers in Medicine;2023-09-08

3. Get me out of here: Sphingosine 1‐phosphate signaling and T cell exit from tissues during an immune response;Immunological Reviews;2023-05-22

4. Insights into phenotypic and functional CD8⁺ T_RM heterogeneity;Immunological Reviews;2023-05-16