1. Genentech Research and Early Development, South San Francisco, 94080 CA, USA
2. Present address: Department of Safety Assessment, Nektar Therapeutics, San Francisco, 94158 CA, USA
3. Present address: Department of Pathology and Laboratory Medicine, Keck School of Medicine of USC, Los Angeles, 90033 CA, USA
4. Present address: Clinical Development and US Operation, Innovent Biologics, South San Francisco, 94080 CA, USA