Monitoring In Vivo Performances of Protein–Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging-Reference-Cited by-同舟云学术

Monitoring In Vivo Performances of Protein–Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging

Published:2022-05-02 Issue:9 Volume:65 Page:6953-6968
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cahuzac Héloïse¹,Sallustrau Antoine²,Malgorn Carole¹,Beau Fabrice¹,Barbe Peggy¹,Babin Victor²,Dubois Steven¹,Palazzolo Alberto²,Thai Robert¹,Correia Isabelle³,Lee Ki Baek⁴,Garcia-Argote Sébastien²,Lequin Olivier³^ORCID,Keck Mathilde¹^ORCID,Nozach Hervé¹,Feuillastre Sophie²^ORCID,Ge Xin⁴,Pieters Gregory²^ORCID,Audisio Davide²^ORCID,Devel Laurent¹^ORCID

Affiliation:

1. Département Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SIMoS, Gif-sur-Yvette 91191, France

2. Département Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SCBM, Gif-sur-Yvette 91191, France

3. Sorbonne Université, Ecole Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules, LBM, Paris 75005, France

4. Institute of Molecular Medicine, University of Texas, Health Science Center at Houston 1825 Pressler St, Houston, Texas 77030, United States

Funder

Commissariat ? l'?nergie Atomique et aux ?nergies Alternatives

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00401

Reference52 articles.

1. Strategies and challenges for the next generation of antibody–drug conjugates

2. Antibody–drug conjugates for cancer

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4. Auristatin Antibody Drug Conjugate Physical Instability and the Role of Drug Payload

5. Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

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