Isocitrate dehydrogenase 1–mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress-Reference-Cited by-同舟云学术

Isocitrate dehydrogenase 1–mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress

Published:2018-07-12 Issue:1 Volume:33 Page:557-571
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Lenting Krissie¹²,Khurshed Mohammed³,Peeters Tom H.⁴,Heuvel Corina N. A. M.¹²,Lith Sanne A. M.²,Bitter Tessa²,Hendriks Wiljan⁵,Span Paul N.⁶,Molenaar Remco J.³,Botman Dennis³,Verrijp Kiek²,Heerschap Arend⁴,Laan Mark⁷,Kusters Benno²,Ewijk Anne¹,Huynen Martijn A.⁸,Noorden Cornelis J. F.³,Leenders William P. J.¹²

Affiliation:

1. Department of BiochemistryRadboud Institute for Molecular Life Sciences Nijmegen The Netherlands

2. Department of PathologyRadboud University Medical Center Nijmegen The Netherlands

3. Department of Medical BiologyCancer Center AmsterdamAcademic Medical Centre Amsterdam The Netherlands

4. Department of Radiology and Nuclear MedicineRadboud University Medical Center Nijmegen The Netherlands

5. Department of Cell BiologyRadboud Institute for Molecular Life Sciences Nijmegen The Netherlands

6. Radiotherapy and Oncoimmunology LaboratoryDepartment of Radiation OncologyRadboud University Medical Center Nijmegen The Netherlands

7. Department of NeurosurgeryRadboud University Medical Center Nijmegen The Netherlands

8. Center for Molecular and Biomolecular InformaticsRadboud Institute for Molecular Life Sciences Nijmegen The Netherlands

Funder

KWF Kankerbestrijding

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.201800907RR

Reference62 articles.

1. Analysis of the IDH1 codon 132 mutation in brain tumors

2. An Integrated Genomic Analysis of Human Glioblastoma Multiforme

3. The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation

4. The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma

5. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

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