The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma-Reference-Cited by-同舟云学术

The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma

Published:2010-02-04 Issue:4 Volume:119 Page:487-494
ISSN:0001-6322
Container-title:Acta Neuropathologica
language:en
Short-container-title:Acta Neuropathol

Author:

Bleeker Fonnet E.,Atai Nadia A.,Lamba Simona,Jonker Ard,Rijkeboer Denise,Bosch Klazien S.,Tigchelaar Wikky,Troost Dirk,Vandertop W. Peter,Bardelli Alberto,Van Noorden Cornelis J. F.

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00401-010-0645-6

Reference38 articles.

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2. Balakrishnan A, Bleeker FE, Lamba S et al (2007) Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma. Cancer Res 67:3545–3550

3. Balss J, Meyer J, Mueller W et al (2008) Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol 116:597–602

4. Biaglow JE, Miller RA (2005) The thioredoxin reductase/thioredoxin system. Cancer Biol Ther 4:6–13

5. Bleeker FE, Lamba S, Leenstra S et al (2009) IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat 30:7–11

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