A Core NRF2 Gene Set Defined Through Comprehensive Transcriptomic Analysis Predicts Selective Drug Resistance and Poor Multicancer Prognosis

Author:

Luo George1ORCID,Kumar Harshita2,Aldridge Kristin3,Rieger Stevie4,Han EunHyang1,Jiang Ethan5,Chan Ernest R.6,Soliman Ahmed7,Mahdi Haider8910,Letterio John J.111213

Affiliation:

1. Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

2. Department of Engineering, Case Western Reserve University, Cleveland, Ohio, USA.

3. Triterpenoid Therapeutics Inc., Tunbridge, Vermont, USA.

4. Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA.

5. Booth School of Business, University of Chicago, Chicago, Illinois, USA.

6. Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.

7. Department of Pediatrics, SUNY Downstate Hospital, Brooklyn, New York, USA.

8. Magee Women’s Research Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

9. Magee Women’s Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

10. Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

11. The Angie Fowler Adolescent and Young Adult Cancer Institute, University Hospitals Rainbow Babies & Children’s Hospital, Cleveland, Ohio, USA.

12. The Case Comprehensive Cancer Center, Cleveland, Ohio, USA.

13. Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.

Publisher

Mary Ann Liebert Inc

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