Glutaminase Inhibitors—Do They Have a Role in the Treatment of Metastatic Clear-Cell Renal Cell Carcinoma?
Author:
Affiliation:
1. Department of Oncology and Metabolism, University of Sheffield, Weston Park Hospital, Sheffield, United Kingdom
Publisher
American Medical Association (AMA)
Subject
Oncology,Cancer Research
Link
https://jamanetwork.com/journals/jamaoncology/articlepdf/2795983/jamaoncology_brown_2022_ic_220013_1666196345.86018.pdf
Reference4 articles.
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2. Telaglenastat plus everolimus in advanced renal cell carcinoma: a randomized, double-blinded, placebo-controlled, phase 2 ENTRATA trial.;Lee;Clin Cancer Res
3. Conditional survival and long-term efficacy with nivolumab plus ipilimumab versus sunitinib in patients with advanced renal cell carcinoma.;Motzer;Cancer,2022
4. Study CB-839 in combination with nivolumab in patients with melanoma, clear cell renal cell carcinoma (ccRCC) and non-small cell lung cancer (NSCLC). ClinicalTrials.gov identifier: NCT02771626. Updated August 19, 2021. Accessed July 27, 2022. https://clinicaltrials.gov/ct2/show/NCT02771626
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3. Design, synthesis, and biological evaluation of novel glutaminase 1 allosteric inhibitors with an alkane chain tail group;European Journal of Medicinal Chemistry;2023-01
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