Glutaminase Inhibitors—Do They Have a Role in the Treatment of Metastatic Clear-Cell Renal Cell Carcinoma?

Author:

Brown Janet E.1

Affiliation:

1. Department of Oncology and Metabolism, University of Sheffield, Weston Park Hospital, Sheffield, United Kingdom

Publisher

American Medical Association (AMA)

Subject

Oncology,Cancer Research

Reference4 articles.

1. Efficacy and safety of telaglenastat plus cabozantinib vs placebo plus cabozantinib in patients with advanced renal cell carcinoma: the CANTATA randomized clinical trial.;Tannir;JAMA Oncol

2. Telaglenastat plus everolimus in advanced renal cell carcinoma: a randomized, double-blinded, placebo-controlled, phase 2 ENTRATA trial.;Lee;Clin Cancer Res

3. Conditional survival and long-term efficacy with nivolumab plus ipilimumab versus sunitinib in patients with advanced renal cell carcinoma.;Motzer;Cancer,2022

4. Study CB-839 in combination with nivolumab in patients with melanoma, clear cell renal cell carcinoma (ccRCC) and non-small cell lung cancer (NSCLC). ClinicalTrials.gov identifier: NCT02771626. Updated August 19, 2021. Accessed July 27, 2022. https://clinicaltrials.gov/ct2/show/NCT02771626

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