Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention-Reference-Cited by-同舟云学术

Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention

Published:2014-08-05 Issue:10 Volume:58 Page:2001-2013
ISSN:1613-4125
Container-title:Molecular Nutrition & Food Research
language:en
Short-container-title:Mol. Nutr. Food Res.

Author:

Beaver Laura M.¹²,Buchanan Alex²³,Sokolowski Elizabeth I.²,Riscoe Allison N.²,Wong Carmen P.¹²,Chang Jeff H.³⁴,Löhr Christiane V.⁵,Williams David E.¹⁴⁶,Dashwood Roderick H.¹⁶⁷,Ho Emily¹²⁴⁸

Affiliation:

1. Linus Pauling Institute; Oregon State University; Corvallis OR USA

2. Biological and Population Health Sciences; Oregon State University; Corvallis OR USA

3. Department of Botany and Plant Pathology; Oregon State University; Corvallis OR USA

4. Center for Genome Research and Biocomputing; Oregon State University; Corvallis OR USA

5. Department of Biomedical Sciences, College of Veterinary Medicine; Oregon State University; Corvallis OR USA

6. Environmental and Molecular Toxicology; Oregon State University; Corvallis OR USA

7. Center for Epigenetics and Disease Prevention, Institute of Biosciences and Technology; Texas A&M Health Science Center; Houston TX USA

8. Moore Family Center; Oregon State University; Corvallis OR USA

Funder

NIH

NIEHS Center

Oregon State University general research fund

Publisher

Wiley

Subject

Food Science,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/mnfr.201400269/fullpdf

Reference46 articles.

1. Cruciferous vegetables intake and risk of prostate cancer: a meta-analysis;Liu;Int. J. Urol.,2012

2. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis;Higdon;Pharmacol. Res.,2007

3. Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells;Singh;Cancer Res.,2009

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