Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Accurately Predicts the Better Bronchodilatory Effect of Inhaled Versus Oral Salbutamol Dosage Forms-Reference-Cited by-同舟云学术

Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Accurately Predicts the Better Bronchodilatory Effect of Inhaled Versus Oral Salbutamol Dosage Forms

Published:2019-02 Issue:1 Volume:32 Page:1-12
ISSN:1941-2711
Container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery
language:en
Short-container-title:Journal of Aerosol Medicine and Pulmonary Drug Delivery

Author:

Boger Elin¹,Fridén Markus¹²

Affiliation:

1. Department of Drug Metabolism and Pharmacokinetics, Respiratory, Inflammation, and Autoimmunity IMED Biotech Unit, AstraZeneca R&D, Gothenburg, Sweden.

2. Translational PKPD, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

Publisher

Mary Ann Liebert Inc

Subject

Pharmacology (medical),Pharmaceutical Science,Pulmonary and Respiratory Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/jamp.2017.1436

Reference46 articles.

1. The Lungs as a Portal of Entry for Systemic Drug Delivery

2. Optimisation of DMPK by the Inhaled Route: Challenges and Approaches

3. Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension

4. Advances in experimental and mechanistic computational models to understand pulmonary exposure to inhaled drugs

5. A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships

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