CFD-PK model for nasal suspension sprays: Validation with human adult in vivo data for triamcinolone acetonide

Author:

Dutta Rabijit,V Kolanjiyil Arun,Walenga Ross L.,Chopski Steven G.,Kaviratna Anubhav,Mohan Abhinav R.,Newman Bryan,Golshahi Laleh,Longest Worth

Funder

U.S. Department of Health and Human Services

US Food and Drug Administration

Publisher

Elsevier BV

Reference75 articles.

1. Anatomically realistic nasal replicas capturing the range of nasal spray drug delivery in adults;Alfaifi;International Journal of Pharmaceutics,2022

2. Sensitivity of pharmacokinetics to differences in the particle size distribution for formulations of locally acting mometasone furoate suspension-based nasal sprays;Amini;Molecular Pharmaceutics,2023

3. Andrieux, F., Terrassin, L., 2011. Method for preparing aqueous pharmaceutical suspensions including a drug that is effective in treating rhinitis. International Patent number WO2012093171A1.Office, E.P. https://patents.google.com/patent/EP2661251A1/en.

4. Numerical evaluation of spray position for improved nasal drug delivery;Basu;Scientific Reports,2020

5. Dissolution in nasal fluid, retention and anti-inflammatory activity of fluticasone furoate in human nasal tissue ex vivo;Baumann;Clinical & Experimental Allergy,2009

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