A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships-Reference-Cited by-同舟云学术

A Novel In Vivo Receptor Occupancy Methodology for the Glucocorticoid Receptor: Toward An Improved Understanding of Lung Pharmacokinetic/Pharmacodynamic Relationships

Published:2015-02-13 Issue:2 Volume:353 Page:279-287
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Boger Elin,Ewing Pär,Eriksson Ulf G.,Fihn Britt-Marie,Chappell Michael,Evans Neil,Fridén Markus

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference24 articles.

1. Anti-inflammatory actions of glucocorticoids: molecular mechanisms;Barnes;Clin Sci (Lond),1998

2. Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: Dopamine D2, serotonin 2A and NK-1 receptors as examples

3. Optimisation of DMPK by the Inhaled Route: Challenges and Approaches

4. Receptor-Based Pharmacokinetic-Pharmacodynamic Analysis of Corticosteroids

5. The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation

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