Assessment of Humoral, Innate, and T-Cell Immune Responses to Adeno-Associated Virus Vectors
Author:
Affiliation:
1. Gene Therapy Program, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Publisher
Mary Ann Liebert Inc
Subject
Genetics (clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2018.038
Reference33 articles.
1. Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy
2. Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing α1-Antitrypsin: Interim Results
3. Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells
4. Adeno-Associated Virus Capsid Structure Drives CD4-Dependent CD8+T Cell Response to Vector Encoded Proteins
5. Adeno-Associated Virus-Mediated Gene Transfer to Nonhuman Primate Liver Can Elicit Destructive Transgene-Specific T Cell Responses
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