Noninvasive Imaging Reveals Stable Transgene Expression in Mouse Airways After Delivery of a Nonintegrating Recombinant Adeno-Associated Viral Vector-Reference-Cited by-同舟云学术

Noninvasive Imaging Reveals Stable Transgene Expression in Mouse Airways After Delivery of a Nonintegrating Recombinant Adeno-Associated Viral Vector

Published:2016-01 Issue:1 Volume:27 Page:60-71
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Vidović Dragana¹,Gijsbers Rik¹²,Quiles-Jimenez Ana¹,Dooley James³⁴,Van den Haute Chris²⁵,Van der Perren Anke⁵,Liston Adrian³⁴,Baekelandt Veerle⁵,Debyser Zeger¹,Carlon Marianne Sylvia¹

Affiliation:

1. Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Flanders, Belgium.

2. Leuven Viral Vector Core, KU Leuven, Flanders, Belgium.

3. Department of Microbiology and Immunology, KU Leuven, Flanders, Belgium.

4. Vlaams Instituut Voor Biotechnologie, Translational Immunology Laboratory, Flanders, Belgium.

5. Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Flanders, Belgium.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2015.109

Reference45 articles.

1. Repeated Aerosolized AAV-CFTR for Treatment of Cystic Fibrosis: A Randomized Placebo-Controlled Phase 2B Trial

2. Phase I Trial of Intranasal and Endobronchial Administration of a Recombinant Adeno-Associated Virus Serotype 2 (rAAV2)-CFTR Vector in Adult Cystic Fibrosis Patients: A Two-Part Clinical Study

3. Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

4. Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes

5. Non-viral vectors for gene-based therapy

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