Factors Affecting the Deposition of Aerosolized Insulin-Reference-Cited by-同舟云学术

Factors Affecting the Deposition of Aerosolized Insulin

Published:2001-09 Issue:3 Volume:3 Page:387-397
ISSN:1520-9156
Container-title:Diabetes Technology & Therapeutics
language:en
Short-container-title:Diabetes Technology & Therapeutics

Author:

Katz Ira M.¹,Schroeter Jeffry D.²,Martonen Ted B.³

Affiliation:

1. Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina

2. Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina

3. Experimental Toxicology Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina; and Division of Pulmonary Diseases, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina; martonen.ted@epa.gov

Publisher

Mary Ann Liebert Inc

Subject

Medical Laboratory Technology,Endocrinology,Endocrinology, Diabetes and Metabolism

Link

http://www.liebertpub.com/doi/pdf/10.1089/15209150152607169

Reference23 articles.

1. Inhaled insulin1Abbreviations: DM, diabetes mellitus; AIDs, acquired immune deficiency syndrome; SC, subcutaneous; DCCT, Diabetes Control and Complications Trial; IDDM, insulin-dependent diabetes mellitus; NIDDM, non-insulin-dependent diabetes mellitus; i.v., intravenous; DDPC, di-decanoyl-alpha-phosphatidylcholine; AUC, area under the curve; INH, inhaled; Cmax, maximum serum concentration; Cmin, minimum serum concentration; Tmax, time of maximum serum concentration; NS, not significant; HbA1c, hemoglobin A1c; OA, oral agent; SD, standard deviation; MDI, metered dose inhaler; DPI, dry powder inhaler; MMAD, mass median aerodynamic diameter; CMC, critical micelle concentration; SR, sustained release; PLGA, poly lactic acid-co-glycolic acid; GI, gastrointestinal, GSD, geometric standard deviation; TLC, total lung capacity; VC, vital capacity; SMK, smokers; MW, molecular weight; MP, melting point.1

2. Effect of terbutaline on mucociliary clearance in asthmatic and healthy subjects after inhalation from a pressurised inhaler and a dry powder inhaler.

3. The effect of aerosol distribution on airway responsiveness to inhaled methacholine in patients with asthma

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