Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Bradycardiac Effects Caused by Co-Administration of Sofosbuvir and Amiodarone-Reference-Cited by-同舟云学术

Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Bradycardiac Effects Caused by Co-Administration of Sofosbuvir and Amiodarone

Published:2018-06 Issue:4 Volume:16 Page:222-229
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Yu Yankun¹²³,Liu Feng¹,He Liuming⁴,Ramakrishna Seeram¹⁵,Zheng Monica²,Bu Lei⁶,Xu Ying¹⁷

Affiliation:

1. Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, Guangzhou, China.

2. Guangdong iPSyte Biosciences Co., Ltd., Guangzhou, China.

3. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

4. Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China.

5. Department of Mechanical Engineering, Faculty of Engineering, National University of Singapore, Singapore, Singapore.

6. Department of Medicine, Leon H. Charney Division of Cardiology, Department of Cell Biology, The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, New York University School of Medicine, New York, New York.

7. Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2017.834

Reference19 articles.

1. Interaction Between Amiodarone and Sofosbuvir-based Treatment for Hepatitis C Virus Infection: Potential Mechanisms and Lessons to be Learned

2. Bradyarrhythmia induced by amiodarone-sofosbuvir co-administration

3. Extreme Bradycardia After First Doses of Sofosbuvir and Daclatasvir in Patients Receiving Amiodarone: 2 Cases Including a Rechallenge

4. Assessment of the clinical cardiac drug-drug interaction associated with the combination of hepatitis C virus nucleotide inhibitors and amiodarone in guinea pigs and rhesus monkeys

5. High-throughput cardiac safety evaluation and multi-parameter arrhythmia profiling of cardiomyocytes using microelectrode arrays

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