A Simple Cell-Based HTS Assay System to Screen for Inhibitors of p53-Hdm2 Protein–Protein Interactions
Author:
Affiliation:
1. Fisher BioImage ApS, Søborg, Denmark.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2006.4.679
Reference10 articles.
1. MDM2 is a Central Node in the p53 Pathway: 12 Years and Counting
2. The MDM2 gene amplification database
3. Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors
4. In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
5. Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
Cited by 18 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Single-Chain Lanthanide Luminescence Biosensors for Cell-Based Imaging and Screening of Protein-Protein Interactions;iScience;2020-09
2. Single-chain lanthanide luminescence biosensors for cell-based imaging and screening of protein-protein interactions;2020-03-11
3. Translocation Biosensors—Versatile Tools to Probe Protein Functions in Living Cells;Methods in Molecular Biology;2017-10-30
4. High Content Screening Biosensor Assay to Identify Disruptors of p53–hDM2 Protein-Protein Interactions;Methods in Molecular Biology;2015
5. High-Content Positional Biosensor Screening Assay for Compounds to Prevent or Disrupt Androgen Receptor and Transcriptional Intermediary Factor 2 Protein–Protein Interactions;ASSAY and Drug Development Technologies;2014-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3