Rat Primary Hepatocytes Show Enhanced Performance and Sensitivity to Acetaminophen During Three-Dimensional Culture on a Polystyrene Scaffold Designed for Routine Use-Reference-Cited by-同舟云学术

Rat Primary Hepatocytes Show Enhanced Performance and Sensitivity to Acetaminophen During Three-Dimensional Culture on a Polystyrene Scaffold Designed for Routine Use

Published:2011-10 Issue:5 Volume:9 Page:475-486
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Schutte Maaike¹,Fox Bridget¹,Baradez Marc-Olivier¹,Devonshire Alison¹,Minguez Jesus¹,Bokhari Maria²,Przyborski Stefan²³,Marshall Damian¹

Affiliation:

1. Department of Molecular and Cell Biology, LGC, Teddington, United Kingdom.

2. School of Biological and Biomedical Science, Durham University, Durham, United Kingdom.

3. Reinnervate Ltd., NETPark Incubator, Sedgefield, United Kingdom.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2011.0371

Reference47 articles.

1. In Vitro Methods in the Prediction of Kinetics of Drugs: Focus on Drug Metabolism

2. Liver Cell Culture Techniques

3. Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

4. Effect of extracellular matrix topology on cell structure, function, and physiological responsiveness: hepatocytes cultured in a sandwich configuration

5. Collagen Type I Gel Cultures of Adult Rat Hepatocytes as a Screening Induction Model for Cytochrome P450-dependent Enzymes

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