1. From the Department of Pharmacology and Toxicology (C.L.B., F.P., G.E.F., G.J., J.G.R.D.M.), Cardiovascular Research Institute Maastricht (CARIM), Universiteit Maastricht, and Department of Functional Developmental Biology (C.L.B., F.P., G.E.F., G.J., J.G.R.D.M.), School of Life Sciences (tUL-SLS), Transnational University of Limburg, Maastricht, The Netherlands; and Department of Pharmacology (M.J.M.), University of Aarhus, Denmark. Present address for F.P. is Department of Pharmacology, INSERM ...