1. From INSERM, INSERM UMR-S U919, Serine Proteases and Pathophysiology of the Neurovascular Unit, GIP Cyceron, University Caen, Caen, France (T.G., C.G., R.G., S.M.D.L., E.E., E.T., D.V., M.G.); and Departments of Neurosurgery (T.G., E.E.), Anesthesiology and Critical Care Medicine (C.G., J.-L.H.), and Neurology (E.T.), Caen University Hospital, Caen, France.