TPT‐004, a Next‐Generation Inhibitor of Tryptophan Hydroxylase, Ameliorates Pulmonary Arterial Hypertension in Rats-Reference-Cited by-同舟云学术

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TPT‐004, a Next‐Generation Inhibitor of Tryptophan Hydroxylase, Ameliorates Pulmonary Arterial Hypertension in Rats

Published:2024-05-21 Issue:10 Volume:13 Page:
ISSN:2047-9980
Container-title:Journal of the American Heart Association
language:en
Short-container-title:JAHA

Author:

Wesolowski Radoslaw¹²^ORCID,Pleimes Dirk²^ORCID,Specker Edgar²³^ORCID,Bader Michael¹²⁴⁵⁶^ORCID

Affiliation:

1. Max‐Delbrück‐Center for Molecular Medicine in the Helmholtz Association (MDC) Berlin Germany

2. Trypto Therapeutics GmbH Berlin Germany

3. Chemical Biology Platform, Leibniz‐Forschungsinstitut für Molekulare Pharmakologie (FMP) Berlin Germany

4. German Center for Cardiovascular Research (DZHK), Partner Site Berlin Berlin Germany

5. Charité—Universitätsmedizin Berlin Berlin Germany

6. University of Lübeck, Institute for Biology Lübeck Germany

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference6 articles.

1. Serotonin and Pulmonary Hypertension; Sex and Drugs and ROCK and Rho

2. Inhibition of serotonin synthesis: A novel therapeutic paradigm

3. A trial design to maximize knowledge of the effects of rodatristat ethyl in the treatment of pulmonary arterial hypertension (ELEVATE 2)

4. Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors

5. Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors

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