1. From the Department of Vascular Medicine (B.v.d.B., G.A.v.M., B.-J.H.v.d.B.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Unilever Research and Development (R.D.), Vlaardingen, The Netherlands; BMEYE BV (B.E.W.), Amsterdam, The Netherlands; Division of Pharmacology and Vascular and Metabolic Diseases (A.H.v.d.M.), Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.