Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase-Reference-Cited by-同舟云学术

Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase

Published:2020-03-15 Issue:6 Volume:31 Page:452-465
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Clarke Akanni¹²,McQueen Philip G.³,Fang Hsiao Yu¹,Kannan Ramakrishnan¹,Wang Victor³,McCreedy Evan³,Buckley Tyler¹,Johannessen Erika¹,Wincovitch Stephen⁴,Giniger Edward¹

Affiliation:

1. National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892

2. Department of Biochemistry and Molecular Medicine, George Washington University School of Medicine/NIH Graduate Partnership Program, Washington, DC 20037

3. Center for Information Technology, National Institutes of Health, Bethesda, MD 20892

4. National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892

Abstract

Live imaging of an axon in its native tissue shows that its growth is protrusive and occurs by stabilization of selected filopodia. Guidance signaling, however, for example, via Abl tyrosine kinase, does not control these morphological properties directly but rather controls actin distribution to determine where filopodial dynamics can occur.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference42 articles.

1. Repulsive Axon Guidance

2. Enabled Negatively Regulates Diaphanous-Driven Actin Dynamics In Vitro and In Vivo

3. Axon guidance in cultured wing discs and disc fragments of Drosophila

4. Dynamic morphogenesis of a pioneer axon in Drosophila and its regulation by Abl tyrosine kinase

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. N-cadherin facilitates trigeminal sensory neuron outgrowth and target tissue innervation;2024-05-21

2. Kinetic trapping organizes actin filaments within liquid-like protein droplets;Nature Communications;2024-04-11

3. Enabled primarily controls filopodial morphology, not actin organization, in the TSM1 growth cone inDrosophila;Molecular Biology of the Cell;2023-07-01

4. A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks;Open Biology;2023-06

5. Kinetic trapping organizes actin filaments within liquid-like protein droplets;2023-05-28