High-Resolution Linear Epitope Mapping of the Receptor Binding Domain of SARS-CoV-2 Spike Protein in COVID-19 mRNA Vaccine Recipients

Author:

Nitahara Yuko1ORCID,Nakagama Yu1,Kaku Natsuko1,Candray Katherine1,Michimuko Yu1,Tshibangu-Kabamba Evariste1,Kaneko Akira1,Yamamoto Hiromasa2,Mizobata Yasumitsu2,Kakeya Hiroshi3,Yasugi Mayo456,Kido Yasutoshi1ORCID

Affiliation:

1. Department of Parasitology & Research Center for Infectious Disease Sciences, Graduate School of Medicine, Osaka City University, Osaka, Japan

2. Department of Traumatology and Critical Care Medicine, Graduate School of Medicine, Osaka City University, Osaka, Japan

3. Department of Infection Control Science, Graduate School of Medicine, Osaka City University, Osaka, Japan

4. Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan

5. Osaka International Research Center for Infectious Diseases, Osaka Prefecture University, Izumisano, Osaka, Japan

6. Asian Health Science Research Institute, Osaka Prefecture University, Izumisano, Osaka, Japan

Abstract

Establishing vaccine-based population immunity has been the key factor in attaining herd protection. Thanks to expedited worldwide research efforts, the potency of mRNA vaccines against the coronavirus disease 2019 (COVID-19) is now incontestable.

Funder

Japan Agency for Medical Research and Development

MEXT | Japan Society for the Promotion of Science

Osaka City University

Center for iPS Cell Research and Application, Kyoto University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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