Abstract
AbstractIn a cohort of BNT162b2 (Pfizer–BioNTech) mRNA vaccine recipients (n = 1,090), we observed that spike-specific IgG antibody levels and ACE2 antibody binding inhibition responses elicited by a single vaccine dose in individuals with prior SARS-CoV-2 infection (n = 35) were similar to those seen after two doses of vaccine in individuals without prior infection (n = 228). Post-vaccine symptoms were more prominent for those with prior infection after the first dose, but symptomology was similar between groups after the second dose.
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Cedars-Sinai Medical Center
Erika J Glazer Family Foundation
Leona M. and Harry B. Helmsley Charitable Trust
F. Widjaja Family Foundation
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
514 articles.
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