Heterogeneity and Evolutionary Tunability of Escherichia coli Resistance against Extreme Acid Stress

Author:

Van Riet Stefanie1,Tadesse Wubishet1,Mortier Julien1,Schlegel Susan23,Simoens Kenneth4,Bernaerts Kristel4,Dal Co Alma23,Aertsen Abram1ORCID

Affiliation:

1. Department of Molecular and Microbial Systems, KU Leuven, Leuven, Belgium

2. Department of Environmental Microbiology, Eawag, Dübendorf, Switzerland

3. Department of Environmental Systems Science, ETH Zurich, Zurich, Switzerland

4. Department of Chemical Engineering, KU Leuven, Leuven, Belgium

Abstract

Acidic environments constitute one of the most important stresses for enteric bacteria and can be encountered in both natural (e.g., host gastrointestinal tract) and manmade (e.g., food processing) environments. The enteric species Escherichia coli harbors many pathovars and is well known for its ability to cope with acid stress.

Funder

Fonds Wetenschappelijk Onderzoek

Onderzoeksraad, KU Leuven

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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