Transcriptome Analysis Reveals an Eicosapentaenoic Acid Accumulation Mechanism in a <i>Schizochytrium</i> sp. Mutant-Reference-Cited by-同舟云学术

Transcriptome Analysis Reveals an Eicosapentaenoic Acid Accumulation Mechanism in a Schizochytrium sp. Mutant

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Ou Ying¹^ORCID,Li Yaqi¹,Feng Shoushuai¹,Wang Qiong²,Yang Hailin¹

Affiliation:

1. Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, WuXi, Jiangsu Province, People’s Republic of China

2. Department of Clinical Laboratory, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, People’s Republic of China

Abstract

Schizochytrium , a marine eukaryotic microorganism, has emerged as a candidate for the commercial production of PUFAs. EPA is an omega-3 PUFA with preventive and therapeutic effects against cardiovascular diseases, schizophrenia, and other disorders.

Funder

Data Center of Management Science, National Natural Science Foundation of China - Peking University

MOST | National Key Research and Development Program of China

Key Experimental Open Project of Ministry of Education of Industrial Biotechnology

Postgraduate Research & Practice Innovation Program of Jiangsu Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00130-23

Reference53 articles.

1. Prescription omega-3 fatty acid products containing highly purified eicosapentaenoic acid (EPA)

2. N-3 polyunsaturated fatty acids and clozapine abrogates poly I: C-induced immune alterations in primary hippocampal neurons

3. The polyunsaturated fatty acid balance in kidney health and disease: A review

4. The synchronized trial on expectant mothers with depressive symptoms by omega-3 PUFAs (SYNCHRO): Study protocol for a randomized controlled trial

5. Improved management is the main driver behind recovery of Northeast Atlantic fish stocks