Identification and Characterization of Human Norovirus NTPase Regions Required for Lipid Droplet Localization, Cellular Apoptosis, and Interaction with the Viral P22 Protein-Reference-Cited by-同舟云学术

Identification and Characterization of Human Norovirus NTPase Regions Required for Lipid Droplet Localization, Cellular Apoptosis, and Interaction with the Viral P22 Protein

Published:2021-09-03 Issue:1 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Yen Ju-Bei¹²,Chen Lee-Wen³⁴,Wei Ling-Huei¹,Hung Chien-Hui¹,Wang Shie-Shan⁴⁵,Lin Chun-Liang⁶,Chang Pey-Jium¹⁶^ORCID

Affiliation:

1. Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang-Gung University, Taoyuan, Taiwan

2. Department of Pediatrics, Chang-Gung Memorial Hospital, Chiayi, Taiwan

3. Department of Respiratory Care, Chang-Gung University of Science and Technology, Chiayi, Taiwan

4. Department of Pediatric Surgery, Chang-Gung Memorial Hospital, Chiayi, Taiwan

5. School of Medicine, Chang-Gung University, Taoyuan, Taiwan

6. Department of Nephrology, Chang-Gung Memorial Hospital, Chiayi, Taiwan

Abstract

Human noroviruses (HuNVs) are the major agent of global gastroenteritis outbreaks. However, due to the lack of an efficient cell culture system for HuNV propagation, functions of the viral-encoded proteins in host cells are still poorly understood.

Funder

Chang Gung Medical Foundation | Chiayi Chang Gung Memorial Hospital

Chang Gung Medical Foundation Chiayi | Chang Gung Memorial Hospital

Ministry of Science and Technology, Taiwan

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00422-21

Reference48 articles.

1. Norovirus