The interplay between lipid droplets and virus infection-Reference-Cited by-同舟云学术

The interplay between lipid droplets and virus infection

Published:2023-07 Issue:7 Volume:95 Page:
ISSN:0146-6615
Container-title:Journal of Medical Virology
language:en
Short-container-title:Journal of Medical Virology

Author:

Qu Yafei¹²,Wang Weili¹²,Xiao Maggie Z. X.³,Zheng Yuejuan⁴⁵,Liang Qiming¹²^ORCID

Affiliation:

1. Center for Immune‐Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

2. Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Department of Immunology and Microbiology Shanghai Jiao Tong University School of Medicine Shanghai China

3. Faculty of Medicine University of Toronto Toronto Ontario Canada

4. The Research Center for Traditional Chinese Medicine, Shanghai Institute of Infectious Disease and Biosecurity Shanghai University of Traditional Medicine Shanghai China

5. Center for Traditional Chinese Medicine and Immunology Research, School of Basic Medical Sciences Shanghai University of Traditional Medicine Shanghai China

Abstract

AbstractAs an intracellular parasite, the virus usurps cellular machinery and modulates cellular metabolism pathways to replicate itself in cells. Lipid droplets (LDs) are universally conserved energy storage organelles that not only play vital roles in maintaining lipid homeostasis but are also involved in viral replication. Increasing evidence has demonstrated that viruses take advantage of cellular lipid metabolism by targeting the biogenesis, hydrolysis, and lipophagy of LD during viral infection. In this review, we summarize the current knowledge about the modulation of cellular LD by different viruses, with a special emphasis on the Hepatitis C virus, Dengue virus, and SARS‐CoV‐2.

Publisher

Wiley

Subject

Infectious Diseases,Virology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmv.28967

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