Highly Specialized Carbohydrate Metabolism Capability in <i>Bifidobacterium</i> Strains Associated with Intestinal Barrier Maturation in Early Preterm Infants-Reference-Cited by-同舟云学术

Highly Specialized Carbohydrate Metabolism Capability in Bifidobacterium Strains Associated with Intestinal Barrier Maturation in Early Preterm Infants

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Ma Bing¹²^ORCID,Sundararajan Sripriya³,Nadimpalli Gita⁴,France Michael¹²^ORCID,McComb Elias¹^ORCID,Rutt Lindsay¹,Lemme-Dumit Jose M.³⁵,Janofsky Elise³,Roskes Lisa S.³^ORCID,Gajer Pawel¹²,Fu Li¹,Yang Hongqiu¹,Humphrys Mike¹,Tallon Luke J.¹,Sadzewicz Lisa¹,Pasetti Marcela F.²³⁵,Ravel Jacques¹²^ORCID,Viscardi Rose M.³

Affiliation:

1. Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA

2. Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

3. Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA

4. Department of Epidemiology, University of Maryland School of Medicine, Baltimore, Maryland, USA

5. Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA

Abstract

Despite improvements in neonatal intensive care, necrotizing enterocolitis (NEC) remains a leading cause of morbidity and mortality. “Leaky gut,” or intestinal barrier immaturity with elevated intestinal permeability, is the proximate cause of susceptibility to NEC. Early detection and intervention to prevent leaky gut in “at-risk” preterm neonates are critical for decreasing the risk of potentially life-threatening complications like NEC.

Funder

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Gerber Foundation

Institute for Clinical and Translational Research, University of Maryland, Baltimore

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.01299-22

Reference133 articles.

1. Understanding the Susceptibility of the Premature Infant to Necrotizing Enterocolitis (NEC)