Outbreak of Carbapenem-Resistant Acinetobacter baumannii Producing the OXA-23 Enzyme in Curitiba, Brazil

Author:

Dalla-Costa Libera M.1,Coelho Juliana M.2,Souza Helena A. P. H. M.1,Castro Maria E. S.1,Stier Christiane J. N.1,Bragagnolo Karin L.1,Rea-Neto Alvaro1,Penteado-Filho Sergio R.3,Livermore David M.2,Woodford Neil2

Affiliation:

1. Hospital de Clínicas da Universidade Federal do Paraná (HC)

2. Antibiotic Resistance Monitoring and Reference Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, Colindale, London NW9 5HT, United Kingdom

3. Hospital Universitário Evangélico de Curitiba (HUEC), Curitiba, Brazil

Abstract

ABSTRACT Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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