Chromosome-Encoded Class D β-Lactamase OXA-23 in Proteus mirabilis-Reference-Cited by-同舟云学术

Chromosome-Encoded Class D β-Lactamase OXA-23 in Proteus mirabilis

Published:2002-06 Issue:6 Volume:46 Page:2004-2006
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Bonnet R.¹,Marchandin H.²,Chanal C.¹,Sirot D.¹,Labia R.³,De Champs C.¹,Jumas-Bilak E.⁴,Sirot J.¹

Affiliation:

1. Laboratoire de Bactériologie, Faculté de Médecine, 63001 Clermont-Ferrand Cedex

2. Laboratoire de Bactériologie, Hôpital Arnaud de Villeneuve, 34295 Montpellier Cedex 5

3. UMR 175, CNRS-MNHN, 29000 Quimper

4. Laboratoire de Bactériologie, Faculté de Pharmacie, 34093 Montpellier Cedex 5, France

Abstract

ABSTRACT Ten nonrepetitive Proteus mirabilis isolates, which were collected over 4 years (1996 to 1999) at the teaching hospital of Clermont-Ferrand, France, produced class D carbapenemase OXA-23. MICs of imipenem were 0.25 to 0.5 μg/ml for these clinical isolates. Molecular typing revealed that the 10 P. mirabilis isolates originated from the same clonal strain. Hybridization of I- Ceu I-generated chromosome fragments with a bla OXA-23 probe showed that the gene was chromosome encoded in the P. mirabilis strain.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.6.2004-2006.2002

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