Bovine Staphylococcus aureus Superantigens Stimulate the Entire T Cell Repertoire of Cattle-Reference-Cited by-同舟云学术

Bovine Staphylococcus aureus Superantigens Stimulate the Entire T Cell Repertoire of Cattle

Published:2018-11 Issue:11 Volume:86 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Wilson Gillian J.¹²,Tuffs Stephen W.¹^ORCID,Wee Bryan A.¹,Seo Keun Seok³^ORCID,Park Nogi³,Connelley Timothy¹,Guinane Caitriona M.¹,Morrison W. Ivan¹,Fitzgerald J. Ross¹

Affiliation:

1. The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom

2. Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom

3. Department of Basic Sciences, Mississippi State University, Mississippi State, Mississippi, USA

Abstract

Superantigens (SAgs) represent a diverse family of bacterial toxins that induce Vβ-specific T cell proliferation associated with an array of important diseases in humans and animals, including mastitis of dairy cows. However, an understanding of the diversity and distribution of SAg genes among bovine Staphylococcus aureus strains and their role in the pathogenesis of mastitis is lacking.

Funder

HHS | NIH | National Institute of General Medical Sciences

RCUK | Biotechnology and Biological Sciences Research Council

RCUK | Medical Research Council

Animal and Plant Quarantine Agency

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00505-18

Reference49 articles.