Comparison of the Yields of Blood Cultures Using Serum or Plasma from Patients with Early Lyme Disease-Reference-Cited by-同舟云学术

Comparison of the Yields of Blood Cultures Using Serum or Plasma from Patients with Early Lyme Disease

Published:2000-04 Issue:4 Volume:38 Page:1648-1650
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Wormser Gary P.¹,Bittker Susan¹,Cooper Denise¹,Nowakowski John¹,Nadelman Robert B.¹,Pavia Charles¹²

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla, New York 10595,1 and

2. New York College of Osteopathic Medicine Microbiology and Immunodiagnostic Laboratory of the New York Institute of Technology, Old Westbury, New York 115682

Abstract

ABSTRACT In an initial experiment, culture-grown Borrelia burgdorferi was added to freshly collected uninfected human blood. This in vitro study demonstrated that more spirochetes were distributed into the plasma than into the serum fraction. In a subsequent clinical study, B. burgdorferi was recovered from plasma cultures of approximately 50% of 42 patients with early Lyme disease associated with erythema migrans. The rate of recovery from plasma cultures was significantly greater than that from serum cultures ( P < 0.001).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.38.4.1648-1650.2000

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