Transcriptional Analysis Shows a Robust Host Response to Toxoplasma gondii during Early and Late Chronic Infection in Both Male and Female Mice-Reference-Cited by-同舟云学术

Transcriptional Analysis Shows a Robust Host Response to Toxoplasma gondii during Early and Late Chronic Infection in Both Male and Female Mice

Published:2019-05 Issue:5 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Garfoot Andrew L.¹,Cervantes Patrick W.¹,Knoll Laura J.¹

Affiliation:

1. Department of Medical Microbiology and Immunology, University of Wisconsin–Madison, Madison, Wisconsin, USA

Abstract

The long-term host effects caused by the protozoan parasite Toxoplasma gondii are poorly understood. High-throughput RNA sequencing analysis previously determined that the host response in the brain was greater and more complex at 28 days than at 10 days postinfection.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

National Science Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00024-19

Reference43 articles.

1. Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii

2. Immunity and Intracellular Infection: Resistance to Bacteria in Mice Infected with a Protozoan