Identification of Amino Acids within Nonstructural Proteins 10 and 14 of the Avian Coronavirus Infectious Bronchitis Virus That Result in Attenuation <i>In Vivo</i> and <i>In Ovo</i>-Reference-Cited by-同舟云学术

Identification of Amino Acids within Nonstructural Proteins 10 and 14 of the Avian Coronavirus Infectious Bronchitis Virus That Result in Attenuation In Vivo and In Ovo

Published:2022-03-23 Issue:6 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Keep Sarah¹^ORCID,Stevenson-Leggett Phoebe¹,Dowgier Giulia¹,Everest Holly¹,Freimanis Graham¹,Oade Michael¹,Hammond John A.¹,Armesto Maria¹,Vila Rut²,Bru Tura²,Geerligs Harm²,Britton Paul¹,Bickerton Erica¹^ORCID

Affiliation:

1. The Pirbright Institute, Surrey, United Kingdom

2. Zoetis, VMRD, Zaventem, Belgium

Abstract

The Gammacoronavirus infectious bronchitis virus (IBV) is the etiological agent of infectious bronchitis, an acute, highly contagious, economically important disease of poultry. Vaccination is achieved using a mixture of live attenuated vaccines for young chicks and inactivated vaccines as boosters for laying hens.

Funder

UKRI | Biotechnology and Biological Sciences Research Council

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.02059-21

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