Effect of Calcium in Assay Medium on D Value of Bacillus stearothermophilus ATCC 7953 Spores-Reference-Cited by-同舟云学术

Effect of Calcium in Assay Medium on D Value of Bacillus stearothermophilus ATCC 7953 Spores

Published:2000-12 Issue:12 Volume:66 Page:5509-5513
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Sasaki Koichi¹,Shintani Hideharu²,Itoh Junpei³,Kamogawa Takuji¹,Kajihara Yousei⁴

Affiliation:

1. Quality Control Department, Misato Plant, Eisai Co., Ltd., Misato-Machi, Kodama-Gun, Saitama 367-0198,1

2. Division of Medical Devices, National Institute of Health Sciences, Setagaya-ku, Tokyo 158-0098,2

3. PPM Manufacturing, Fukushima Plant, Nippon Becton Dickinson Company, Ltd., Tsuchifune, Fukushima City, Fukushima 960-2152,3 and

4. Life Tech Division, Nihon Pharmaceutical Co., Ltd., Sumiyoshi-cho, Izumisano City, Osaka 598-8558,4 Japan

Abstract

ABSTRACT The D value of commercial biological indicator spore strips using Bacillus stearothermophilus ATCC 7953 was increased by higher calcium concentrations in assay media. The calcium concentration in assay media varied among the manufacturers. The calcium concentration in assay media is an important factor to consider to minimize the variation of D value.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.66.12.5509-5513.2000

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