Regulating, Measuring, and Modeling the Viscoelasticity of Bacterial Biofilms

Author:

Charlton Samuel G. V.1,White Michael A.2,Jana Saikat1,Eland Lucy E.2,Jayathilake Pahala Gedara1,Burgess J. Grant3,Chen Jinju1,Wipat Anil2,Curtis Thomas P.1

Affiliation:

1. School of Engineering, Newcastle University, Newcastle upon Tyne, United Kingdom

2. Interdisciplinary Computing & Complex BioSystems Research Group, School of Computing, Newcastle University, Newcastle upon Tyne, United Kingdom

3. School of Natural & Environmental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom

Abstract

Biofilms occur in a broad range of environments under heterogeneous physicochemical conditions, such as in bioremediation plants, on surfaces of biomedical implants, and in the lungs of cystic fibrosis patients. In these scenarios, biofilms are subjected to shear forces, but the mechanical integrity of these aggregates often prevents their disruption or dispersal.

Funder

Orthopaedics Research United Kingdom

RCUK | Natural Environment Research Council

RCUK | Engineering and Physical Sciences Research Council

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference141 articles.

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4. Bacterial biofilms: from the Natural environment to infectious diseases

5. Flemming H-C, Neu TR, Wingender J. 2016. The perfect slime: microbial extracellular polymeric substances (EPS). IWA Publishing, London, United Kingdom.

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